In what we all hope is a sign of things to come, Sergei Bobrovsky made 26 saves and added three more in the shootout to blank the Bolts.
The Panthers won three of its last four games to finish the exhibition season with a 3-4-1 record.
Andrei Vasilevskiy stopped 28 shots for the Lightning, who finished the preseason 2-3-2
Despite not playing with his usual linemates, Evgenii Dadonov registered a game-high seven shots on goal.
Riley Stillman logged 19:52 TOI and had two shots on goal and three hits and took an unsportsmanlike conduct minor.
Josh Brown played 17:45 and registered one shot, two hits, one takeaway and blocked one shot.
Owen Tippett had three shots on goal and three takeaways in 18:37 TOI.
Dominic Toninato dished out a game-high five hits in 11:14 TOI.
Denis Malgin logged 18:52 TOI and finished with two shots, one hit, one block and a takeaway.
Dryden Hunt played exactly 15 minutes and registered two shots on goal.
Jayce Hawryluk had one shot on goal and two hits in 10:22 TOI.